Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.51 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.45 |
| ▸ | CA4 | P22748 | 10/20 | 0.45 |
| ▸ | CA9 | Q16790 | 10/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241594 | 1.00 | TACR1 (0.51) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL8475431 | 0.91 | TACR1 (0.60) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL8475440 | 0.90 | TACR1 (0.43) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL9236248 | 0.90 | TACR1 (0.43) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL8476010 | 0.87 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL8474867 | 0.87 | TACR1 (0.46) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL8479494 | 0.86 | TACR1 (0.47) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL9236265 | 0.86 | TACR1 (0.47) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL8476085 | 0.86 | TACR1 (0.58) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL9236786 | 0.85 | TACR1 (0.44) | TACR1CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883098-A | USED AS TACHYKININ ANTAGONISTS IN THE TREATMENT OF RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND INFLAMMATORY DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| US-5670505-A | TACHYKIKIN ANTAGONIST FOR RESPIRATORY DISEASES, OPHTHALMIC DISEASES AND ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |