Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475440 | 1.00 | TACR1 (0.43) | TACR1GAAGFERRAB9ACA1 | |
| SCHEMBL8478209 | 0.90 | TACR1 (0.51) | TACR1CA1CA2CA4CA9 | |
| SCHEMBL9241594 | 0.90 | TACR1 (0.51) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL8480146 | 0.87 | TACR1 (0.43) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL9233966 | 0.87 | TACR1 (0.43) | TACR1CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL7556699 | 0.85 | TACR1 (0.42) | TACR1 | |
| SCHEMBL9235672 | 0.83 | NAMPT (0.44) | TACR1NAMPT | |
| SCHEMBL8836563 | 0.83 | NAMPT (0.44) | TACR1NAMPT | |
| SCHEMBL9234523 | 0.83 | NAMPT (0.44) | TACR1NAMPT | |
| SCHEMBL9235668 | 0.83 | NAMPT (0.44) | TACR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |