Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478279 | 1.00 | SRD5A2 (0.55) | SRD5A2SRD5A1AR | |
| SCHEMBL8016958 | 0.88 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL7386216 | 0.88 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL7380929 | 0.88 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8016669 | 0.88 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8016963 | 0.88 | SRD5A2 (0.58) | SRD5A2SRD5A1AR | |
| SCHEMBL8016811 | 0.86 | SRD5A2 (0.49) | SRD5A2SRD5A1AR | |
| SCHEMBL8017034 | 0.85 | SRD5A2 (0.47) | SRD5A2SRD5A1AR | |
| SCHEMBL8016230 | 0.85 | SRD5A2 (0.47) | SRD5A2SRD5A1AR | |
| SCHEMBL8018780 | 0.85 | SRD5A2 (0.47) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998427-A | REDUCTASE INHIBITOR | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| US-5977126-A | ANTIANGROGENS, ENZYME INHBITORS | GLAXO WELLCOME INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5817818-A | THERAPY OF ANDROGEN RESPONSIVE DISEASES | GLAXO WELLCOME INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0719277-B1 | ANDROSTENONES | GLAXO WELLCOME INC (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0719277-A1 | ANDROSTENONES | GLAXO WELLCOME INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007926-A1 | ANDROSTENONES | GLAXO WELLCOME INC. (US) | 1995-03-23 | — | — | WO | disclosed |