SCHEMBL8478404

SCHEMBL8478404

C=CCN(C)CCCCCCOc1ccc2c(c1)c(-c1ccc(Br)cc1)nc(=O)n2C

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LSS P48449 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760902 0.93 LSS (0.75) LSS
SCHEMBL8760699 0.80 LSS (1.00) LSS
SCHEMBL8760752 0.78 LSS (1.00) LSS
SCHEMBL8478402 0.77 CASR (0.40) LSS
SCHEMBL8760843 0.76 LSS (0.76) LSS
SCHEMBL9068260 0.76 LSS (0.89) LSS
SCHEMBL8759845 0.76 LSS (1.00) LSS
SCHEMBL8762179 0.76 LSS (1.00) LSS
SCHEMBL4311426 0.75 LSS (1.00) LSS
SCHEMBL8760862 0.75 LSS (1.00) LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856503-A ANTICHOLESTEROL AGENTS HOFFMANN-LA ROCHE INC. (US) 1999-01-05 US disclosed