SCHEMBL8478402

SCHEMBL8478402

C=CCN(C)C(CCCCC)Oc1ccc2c(c1)c(-c1ccc(Br)cc1)nc(=O)n2C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CASR P41180 8/20 0.40
LSS P48449 12/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8478404 0.77 LSS (0.67) LSS
SCHEMBL8760902 0.70 LSS (0.75) LSS
SCHEMBL8478407 0.69 LSS (0.41) CASRLSS
SCHEMBL8483917 0.66 LSS (0.41) LSS
SCHEMBL8483828 0.65 LSS (0.44) LSS
SCHEMBL8482869 0.63 LSS (0.42) LSS
SCHEMBL8478934 0.62 LSS (0.44) LSS
Fumaric Acid SCHEMBL8481419 0.62 LSS (0.47) LSS
SCHEMBL8485026 0.62 LSS (0.39) LSS
Fumaric Acid SCHEMBL8482996 0.62 LSS (0.58) LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856503-A ANTICHOLESTEROL AGENTS HOFFMANN-LA ROCHE INC. (US) 1999-01-05 US disclosed