Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674400 | 0.86 | F2 (0.56) | F2CNR1CNR2HTR6CA1 | |
| SCHEMBL8476642 | 0.85 | F2 (0.61) | F2MEN1KMT2A | |
| SCHEMBL8479909 | 0.80 | F2 (0.53) | F2CNR1CNR2HTR6F10 | |
| SCHEMBL7442037 | 0.80 | F2 (0.58) | F2F10CTRCPRSS2 | |
| SCHEMBL8481688 | 0.79 | F2 (0.56) | F2HTR6CTRCMEN1KMT2A | |
| SCHEMBL5674392 | 0.79 | F2 (0.66) | F2F10CTRCPRSS2 | |
| SCHEMBL5674385 | 0.78 | F2 (0.70) | F2CTRCPRSS2 | |
| SCHEMBL8481393 | 0.78 | F2 (0.55) | F2CNR1CNR2F10CTRC | |
| SCHEMBL5176359 | 0.77 | CA1 (0.53) | F2CNR1CNR2HTR6CA1 | |
| SCHEMBL8479198 | 0.76 | F2 (0.57) | F2CNR2CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |