Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.61 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.46 |
| ▸ | PRKCG | P05129 | 4/20 | 0.46 |
| ▸ | PRKCB | P05771 | 4/20 | 0.46 |
| ▸ | PRKCA | P17252 | 4/20 | 0.46 |
| ▸ | PRKCH | P24723 | 4/20 | 0.46 |
| ▸ | PRKCI | P41743 | 4/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 3/20 | 0.44 |
| ▸ | PRKACG | P22612 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674500 | 0.88 | F2 (0.63) | F2PRKD3PRKCGPRKCBPRKCA | |
| Orcinol SCHEMBL5676130 | 0.86 | F2 (0.61) | F2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL8478443 | 0.85 | F2 (0.53) | F2MEN1KMT2A | |
| SCHEMBL8483618 | 0.82 | F2 (0.58) | F2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5674536 | 0.82 | F2 (0.75) | F2P2RX7 | |
| SCHEMBL6749583 | 0.81 | F2 (0.77) | F2 | |
| SCHEMBL5673005 | 0.81 | F2 (0.68) | F2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL8481901 | 0.81 | F2 (0.61) | F2LMNASMN1; SMN2P2RX7 | |
| SCHEMBL5698943 | 0.79 | P2RX7 (0.52) | F2PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29566137 | 0.79 | P2RX7 (0.52) | F2PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |