Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | UGCG | Q16739 | 7/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 7/20 | 0.47 |
| ▸ | GBA1 | P04062 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LCT | P09848 | 4/20 | 0.41 |
| ▸ | SI | P14410 | 4/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31549217 | 1.00 | MEN1 (0.60) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL15516358 | 0.98 | MEN1 (0.62) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL12903278 | 0.98 | MEN1 (0.62) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL334794 | 0.98 | MEN1 (0.62) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL334897 | 0.93 | MEN1 (0.64) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL8483039 | 0.87 | TSHR (0.58) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL334304 | 0.86 | MEN1 (0.68) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL2186409 | 0.86 | MEN1 (0.68) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL29606950 | 0.86 | MEN1 (0.68) | MEN1KMT2AUGCGGBA2GBA1 | |
| SCHEMBL2186406 | 0.86 | MEN1 (0.68) | MEN1KMT2AUGCGGBA2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5871709-A | TETRAAZACYCLODODECANE COMPOUNDS SUBSTITUTED WITH ALKYL CARBOXY COMPOUNDS FOR CARDIOVASCULAR DISORDERS AND BRAIN TUMORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |
| EP-0485045-B1 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |