Sugi Predict

Sugi Predict / Compounds / SCHEMBL2186409

SCHEMBL2186409

SCHEMBL2186409

c1ccc(COCCC2CO2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.68
▸ KMT2A Q03164 1/20 0.68
▸ TSHR P16473 1/20 0.50
▸ TAAR1 Q96RJ0 1/20 0.46
▸ PDE4D Q08499 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ LTA4H P09960 1/20 0.41
▸ NAAA Q02083 1/20 0.40
▸ GBA1 P04062 2/20 0.39
▸ UGCG Q16739 2/20 0.39
▸ GBA2 Q9HCG7 2/20 0.39
▸ MGLL Q99685 2/20 0.39
▸ AGTR2 P50052 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29606950 1.00 MEN1 (0.68) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL2186406 1.00 MEN1 (0.68) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL334304 1.00 MEN1 (0.68) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL334897 0.89 MEN1 (0.64) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL15516358 0.88 MEN1 (0.62) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL334794 0.88 MEN1 (0.62) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL12903278 0.88 MEN1 (0.62) MEN1KMT2ATSHRTAAR1PDE4D
SCHEMBL31549217 0.86 MEN1 (0.60) MEN1KMT2ATSHRTAAR1TDP1
SCHEMBL8478562 0.86 MEN1 (0.60) MEN1KMT2ATSHRTAAR1TDP1
SCHEMBL14250237 0.86 MEN1 (0.55) MEN1KMT2ATSHRTAAR1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 — — CN claimed
US-11710854-B2 Functional epoxides in catalyst-based electrolyte compositions for Li-ion batteries ENEVATE CORPORATION (US) 2023-07-25 — — US claimed
US-20220140392-A1 FUNCTIONAL EPOXIDES IN CATALYST-BASED ELECTROLYTE COMPOSITIONS FOR LI-ION BATTERIES ENEVATE CORPORATION 2022-05-05 — — US claimed
WO-2022093797-A1 FUNCTIONAL EPOXIDES IN CATALYST-BASED ELECTROLYTE COMPOSITIONS FOR LI-ION BATTERIES ENEVATE CORPORATION (US) 2022-05-05 — — WO claimed
EP-0988789-B1 Reduced pitting microbicide formulation ROHM & HAAS (US) 2003-08-27 — — EP claimed
EP-0988789-A2 Reduced pitting microbicide formulation ROHM AND HAAS COMPANY (US) 2000-03-29 — — EP claimed
US-20260070908-A1 NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE UNIV TEMPLE (US) 2026-03-12 — — US disclosed
US-12559494-B2 Functionalized lactams as modulators of the 5-hydroxytryptamine receptor 7 and their method of use TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-02-24 — — US disclosed
US-12552757-B2 NRF2-activating compound SENJU PHARMACEUTICAL CO., LTD. (JP) 2026-02-17 — — US disclosed
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof AGAIN BIO APS (DK) 2025-07-31 — — US disclosed
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof GENOMATICA, INC. (US) 2025-05-20 — — US disclosed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 — — CN disclosed
EP-4519265-A1 IRREVERSIBLE MUTEGFR INHIBITORS Bayer Aktiengesellschaft (DE) 2025-03-12 — — EP disclosed
WO-1997032879-A1 7-ALKYL-PYRROLO[2,3-d]PYRIMIDINES NOVARTIS AG (CH) 1997-09-12 — — WO disclosed
US-5530143-A REDUCTION OF (3S)-3-HYDROXYOCTANEDIOIC DIESTER WITH COMPLEX HYDRIDE BASF AKTIENGESELLSCHAFT (DE) 1996-06-25 — — US disclosed
US-5127934-A STABILIZED COMPOSITIONS COMPRISING ISOTHIAZOLONES AND EPOXIDES ROHM AND HAAS COMPANY (US) 1992-07-07 — — US disclosed
EP-0342852-B1 ORGANIC STABILIZERS ROHM AND HAAS COMPANY (US) 1991-12-11 — — EP disclosed
EP-0342852-A1 Organic stabilizers ROHM AND HAAS COMPANY (US) 1989-11-23 — — EP disclosed
EP-0121972-B1 N-ARYL-ALPHA-AMINO-CARBOXAMIDES JANSSEN PHARMACEUTICA N.V. (BE) 1989-05-24 — — EP disclosed
EP-0121972-A2 N-aryl-alpha-amino-carboxamides JANSSEN PHARMACEUTICA N.V. (BE) 1984-10-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559494-B2 Functionalized lactams as modulators of the 5-hydroxytryptamine receptor 7 and their method of use HTR1B, HTR7, HTR6 MEN1 3743/4885KMT2A 3250/4885TSHR 92/4885
US-20250243143-A1 1,3-Fatty Diol Compounds And Derivatives Thereof DGAT1, DGAT2, DSG1 MEN1 3510/4885KMT2A 1008/4885TSHR 4725/4885
US-12304883-B2 1,3-fatty diol compounds and derivatives thereof DGAT1, DGAT2, DSG1 MEN1 3510/4885KMT2A 1008/4885TSHR 4725/4885
US-20260070908-A1 NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE HTR7, HTR2C, TPH2 MEN1 3067/4885KMT2A 1855/4885TSHR 170/4885
US-12552757-B2 NRF2-activating compound NFE2L2, NFE2, KEAP1 MEN1 4783/4885KMT2A 1330/4885TSHR 2086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.