Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8479203 | 0.99 | HCRTR1 (0.45) | HCRTR1MEN1KMT2AATMTERT | |
| SCHEMBL8486845 | 0.90 | HCRTR1 (0.49) | HCRTR1MEN1KMT2AATMTERT | |
| Hydrochloric Acid SCHEMBL8855089 | 0.88 | HCRTR1 (0.48) | HCRTR1MEN1KMT2AATMTERT | |
| SCHEMBL8483674 | 0.88 | HCRTR1 (0.53) | HCRTR1MEN1KMT2AATMTERT | |
| Hydrochloric Acid SCHEMBL8484158 | 0.87 | HCRTR1 (0.52) | HCRTR1MEN1KMT2AATMTERT | |
| SCHEMBL3291028 | 0.86 | TERT (0.51) | HCRTR1MEN1KMT2AATMTERT | |
| Hydrochloric Acid SCHEMBL8485102 | 0.84 | TERT (0.50) | HCRTR1MEN1KMT2AATMTERT | |
| SCHEMBL8484557 | 0.77 | SMN1; SMN2 (0.41) | HCRTR1MEN1KMT2AATMTERT | |
| SCHEMBL8483708 | 0.77 | KDM4E (0.56) | HCRTR1TERTSMN1; SMN2ACHEL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8483610 | 0.76 | SMN1; SMN2 (0.40) | HCRTR1MEN1KMT2AATMTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681958-A | TREATMENT OF DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | claimed |
| US-5925647-A | TREATMENT OF INSULIN NON-INSULIN DEPENDENT DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5681958-A | TREATMENT OF DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |