Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478592 | 1.00 | ADRB3 (0.58) | ADRB3ADRB1ALOX15ADRB2LMNA | |
| SCHEMBL8478597 | 1.00 | ADRB3 (0.58) | ADRB3ADRB1ALOX15ADRB2LMNA | |
| SCHEMBL667470 | 0.91 | ALOX15 (0.69) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| SCHEMBL667469 | 0.91 | ALOX15 (0.69) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| SCHEMBL667471 | 0.91 | ALOX15 (0.69) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6136778 | 0.90 | ALOX15 (0.71) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6136770 | 0.90 | ALOX15 (0.71) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL6136774 | 0.90 | ALOX15 (0.71) | ADRB3ADRB1ALOX15ADRB2CYP1A2 | |
| SCHEMBL3704286 | 0.85 | ADRB3 (0.60) | ADRB3ADRB1ALOX15ADRB2 | |
| SCHEMBL3704284 | 0.85 | ADRB3 (0.60) | ADRB3ADRB1ALOX15ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977124-A | β-adrenergic agonists | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0824519-A1 | BETA-ADRENERGIC AGONISTS | PFIZER INC. (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035671-A1 | β-ADRENERGIC AGONISTS | PFIZER INC. (US) | 1996-11-14 | — | — | WO | disclosed |