Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479278 | 0.90 | AR (0.59) | AR | |
| SCHEMBL1715663 | 0.89 | AR (0.53) | AR | |
| SCHEMBL1716338 | 0.88 | AR (0.63) | AR | |
| SCHEMBL4029285 | 0.82 | AR (0.62) | AR | |
| SCHEMBL1773546 | 0.81 | AR (0.68) | AR | |
| SCHEMBL1716198 | 0.79 | AR (0.56) | AR | |
| SCHEMBL21155744 | 0.78 | AR (0.57) | AR | |
| SCHEMBL14620477 | 0.77 | AR (0.61) | AR | |
| SCHEMBL1716347 | 0.77 | AR (0.61) | AR | |
| SCHEMBL8926833 | 0.76 | AR (0.57) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958936-A | FOR INDUCING ANTIANDROGENIC ACTIVITY IN WARM-BLOODED ANIMALS, INCLUDING HUMANS | HOECHST MARION ROUSSEL (FR) | 1999-09-28 | — | — | US | claimed |
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | disclosed |