Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20984021 | 0.89 | USP2 (0.43) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL1488353 | 0.88 | USP2 (0.48) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL17619470 | 0.87 | ESR2 (0.51) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL2292608 | 0.83 | USP2 (0.52) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL31080015 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL13801225 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL120243 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL17080478 | 0.81 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL13283565 | 0.81 | ESR2 (0.49) | USP2SMN1; SMN2ESR2NR1H2MAPK1 | |
| SCHEMBL21876055 | 0.80 | USP2 (0.50) | USP2SMN1; SMN2ESR2NR1H2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939268-A | DIELS-ALDER REACTION PRODUCT OF A DIENE AND A DIENOPHILE; CHEMICAL INTERMEDIATES FOR DRUGS, SOLID PHASE SYNTHESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| US-5939268-A | DIELS-ALDER REACTION PRODUCT OF A DIENE AND A DIENOPHILE; CHEMICAL INTERMEDIATES FOR DRUGS, SOLID PHASE SYNTHESIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | disclosed |