Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485500 | 0.93 | LSS (0.61) | LSSMAPTALDH2MAOAMAOB | |
| SCHEMBL5038084 | 0.92 | LSS (0.59) | LSSMAPTALDH2MAOAMAOB | |
| SCHEMBL5035549 | 0.88 | LSS (0.58) | LSSMAPTALDH2MAOAMAOB | |
| SCHEMBL8486489 | 0.87 | LSS (0.53) | LSSMAPTKDM4ETP53 | |
| SCHEMBL5038215 | 0.84 | LSS (0.49) | LSSMAPTALDH2MAOAMAOB | |
| SCHEMBL5038200 | 0.81 | LSS (0.47) | LSSALDH2MAOAMAOBNOS1 | |
| SCHEMBL8760823 | 0.81 | LSS (0.81) | LSS | |
| Fumaric Acid SCHEMBL8479463 | 0.80 | LSS (0.64) | LSSKDM4E | |
| SCHEMBL5139832 | 0.79 | LSS (0.64) | LSSMAPTMAOBKMT2A | |
| SCHEMBL5140362 | 0.79 | LSS (0.68) | LSSMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |