SCHEMBL8760823

SCHEMBL8760823

C=CCN(C)CCCCCCOc1ccc(C2=NS(=O)(=O)c3cc(Br)ccc32)cc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LSS P48449 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5139998 0.94 LSS (0.88) LSS
SCHEMBL5140651 0.91 LSS (0.84) LSS
SCHEMBL5140149 0.86 LSS (0.74) LSS
SCHEMBL5140900 0.84 LSS (0.71) LSS
SCHEMBL8478769 0.81 LSS (0.54) LSS
SCHEMBL5140725 0.81 LSS (0.69) LSS
SCHEMBL5140362 0.80 LSS (0.68) LSS
SCHEMBL5140931 0.80 LSS (0.71) LSS
SCHEMBL5139772 0.80 LSS (0.68) LSS
SCHEMBL8486489 0.79 LSS (0.53) LSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778271-A2 Aminoalkyl-substituted benzo-heterocyclic compounds F. HOFFMANN-LA ROCHE AG (CH) 1997-06-11 EP claimed
EP-0778271-A2 Aminoalkyl-substituted benzo-heterocyclic compounds F. HOFFMANN-LA ROCHE AG (CH) 1997-06-11 EP disclosed