Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 12/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478986 | 1.00 | LSS (0.46) | LSSPPARDMEN1KMT2ASRD5A2 | |
| SCHEMBL7686037 | 0.85 | LSS (0.53) | LSSMEN1KMT2ALMNAMAPT | |
| SCHEMBL7686041 | 0.85 | LSS (0.53) | LSSMEN1KMT2ALMNAMAPT | |
| SCHEMBL8903282 | 0.84 | LSS (0.53) | LSSPPARDMEN1KMT2ASRD5A2 | |
| SCHEMBL8045167 | 0.84 | LSS (0.53) | LSSPPARDMEN1KMT2ASRD5A2 | |
| SCHEMBL8761374 | 0.82 | LSS (0.74) | LSSMEN1KMT2A | |
| SCHEMBL8478859 | 0.82 | LSS (0.52) | LSSMEN1KMT2A | |
| SCHEMBL7685512 | 0.82 | LSS (0.62) | LSSPPARDMEN1KMT2ASRD5A2 | |
| SCHEMBL7685521 | 0.82 | LSS (0.62) | LSSPPARDMEN1KMT2ASRD5A2 | |
| SCHEMBL7687942 | 0.81 | LSS (0.56) | LSSMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0778271-A2 | Aminoalkyl-substituted benzo-heterocyclic compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |