Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582044 | 0.82 | HTT (0.56) | HTTHTR6PTGER1KDM4ECPT2 | |
| SCHEMBL8481500 | 0.79 | HTT (0.75) | HTTHTR6PTGER1KDM4EHSD17B10 | |
| SCHEMBL8483648 | 0.78 | CFD (0.40) | HTTHTR6 | |
| SCHEMBL8483654 | 0.78 | CFD (0.40) | HTTHTR6 | |
| SCHEMBL8482994 | 0.78 | DYRK1A (0.58) | HTTHTR6KDM4ECPT2CPT1A | |
| SCHEMBL2002570 | 0.75 | TRPV1 (0.48) | HTR6CPT2CPT1ACPT1BKMT2A | |
| SCHEMBL5415657 | 0.73 | F2RL3 (0.54) | HTTHTR6KDM4ECPT2CPT1A | |
| SCHEMBL8479325 | 0.72 | MAPT (0.60) | HTTPTGER1L3MBTL1DYRK1AKMT2A | |
| SCHEMBL18002368 | 0.71 | MAPT (0.60) | KDM4EALDH1A1KMT2AMEN1IDO1 | |
| SCHEMBL18002373 | 0.71 | MAPT (0.60) | KDM4EALDH1A1KMT2AMEN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |