Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715277 | 0.81 | ALDH1A1 (0.39) | CSNK2A1 | |
| SCHEMBL22462465 | 0.81 | ALDH1A1 (0.31) | CSNK2A1 | |
| SCHEMBL10179972 | 0.68 | CSNK2A1 (1.00) | CSNK2A1AHR | |
| SCHEMBL22655868 | 0.67 | AXL (0.56) | CSNK2A1AXL | |
| SCHEMBL14889487 | 0.67 | CSNK2A1 (0.48) | CSNK2A1AHRHAVCR2 | |
| SCHEMBL17351236 | 0.67 | CSNK2A1 (0.48) | CSNK2A1AHRHAVCR2AXL | |
| SCHEMBL3850787 | 0.66 | AHR (0.58) | CSNK2A1AHR | |
| SCHEMBL207489 | 0.64 | F7 (0.50) | AHRHAVCR2 | |
| SCHEMBL207737 | 0.64 | CYP2A6 (0.50) | CSNK2A1AHR | |
| SCHEMBL11282194 | 0.64 | AHR (0.55) | CSNK2A1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925647-A | TREATMENT OF INSULIN NON-INSULIN DEPENDENT DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5681958-A | TREATMENT OF DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |