Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | ANPEP | P15144 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027805 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL1257236 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL475537 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL85067 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL1412106 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL5408514 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL85695 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL3789795 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL611185 | 1.00 | CYP3A4 (0.53) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 | |
| SCHEMBL3188827 | 0.90 | CYP1A2 (0.52) | CYP3A4CYP1A2POLBCYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874590-A | Preparation method of drug intermediate difluoro methyl ether proline derivative without heavy metal participation | 安庆融创生物科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119505138-A | Chiral covalent organic framework mimic enzyme catalyst and preparation method and application thereof | 浙江工业大学 | 2025-02-25 | — | — | CN | claimed |
| CN-117399071-A | Chiral bifunctional catalyst UiO-67-Pro-Ru and preparation method and application thereof | 东南大学 | 2024-01-16 | — | — | CN | claimed |
| CN-115286559-B | Preparation method of key intermediate of anti-new crown drug Pa Luo Weide | 上海再启生物技术有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-116199894-A | Inner-winding chiral polymer and preparation method and application thereof | 中山大学 | 2023-06-02 | — | — | CN | claimed |
| CN-116063215-A | Synthesis method of 4-amino-L-proline | 南京安淮创新药物研究院有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115806518-A | Synthesis method of N-Boc-4-oxo-proline methyl ester | 南京安伦化工科技有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-115286559-A | Preparation method of anti-new crown drug Parovirid key intermediate | 上海再启生物技术有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-105175491-A | Hydroxyproline skeleton-containing polypeptide NS3 serine protease inhibitor, preparation method and applications thereof | UNIV SHANDONG | 2015-12-23 | — | — | CN | claimed |
| CN-104844495-A | Synthesis method of (2S,4S)-4-thiophenyl-L-proline hydrochloride | UNIV WUHAN TECH | 2015-08-19 | — | — | CN | claimed |
| CN-103396351-A | Pyrrolidone Bc1-2 protein small-molecule inhibitor compound, and preparation, pharmaceutical composition and pharmaceutical use thereof | UNIV SHANDONG | 2013-11-20 | — | — | CN | claimed |
| EP-4746963-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747260-A1 | MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| EP-4743465-A1 | BICYCLIC MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| EP-4743459-A1 | BICYCLIC AND MONOCYCLIC TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-0367130-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| US-4822787-A | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid compounds and antimicrobial activity thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |
| EP-0272456-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |