Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 13/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 13/20 | 0.52 |
| ▸ | PDE4A | P27815 | 5/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801177 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL10353452 | 0.84 | SMN1; SMN2 (0.81) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL11035016 | 0.80 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL9687996 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL927560 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL6331085 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL2846257 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL7273533 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL8302890 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R | |
| SCHEMBL10556720 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTLMNANPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883090-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-16 | — | — | US | disclosed |