Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 6/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | BRD1 | O95696 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 2/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479944 | 0.98 | MAPT (0.37) | MAPTTP53MEN1KMT2ABRPF1 | |
| SCHEMBL8482589 | 0.93 | RXFP1 (0.34) | MAPTTP53MEN1KMT2ABRPF1 | |
| SCHEMBL8483454 | 0.89 | MEN1 (0.35) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL8523535 | 0.89 | KMT2A (0.40) | MAPTTP53MEN1KMT2ABRPF1 | |
| SCHEMBL8667926 | 0.87 | MEN1 (0.37) | MAPTTP53MEN1KMT2ARXFP1 | |
| Hydrochloric Acid SCHEMBL8663917 | 0.86 | MEN1 (0.36) | MAPTTP53MEN1KMT2ARXFP1 | |
| SCHEMBL8667142 | 0.86 | MAPT (0.36) | MAPTTP53MEN1KMT2ABRPF1 | |
| SCHEMBL8573190 | 0.86 | MEN1 (0.35) | MAPTMEN1KMT2ARXFP1RAB9A | |
| SCHEMBL8653102 | 0.86 | HCRTR1 (0.35) | MAPTTP53MEN1KMT2ABRPF1 | |
| SCHEMBL8504394 | 0.86 | MEN1 (0.37) | MAPTTP53MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-H1729-H | Method for preparing compounds employing solid phase synthesis and novel linker-resin | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |