Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483454 | 0.90 | MEN1 (0.35) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL8480001 | 0.89 | MAPT (0.38) | KMT2AMEN1BRPF1TP53POLB | |
| SCHEMBL8653102 | 0.88 | HCRTR1 (0.35) | KMT2AMEN1BRPF1TP53SMN1; SMN2 | |
| SCHEMBL8654141 | 0.87 | POLB (0.37) | KMT2AMEN1BRPF1POLBALDH1A1 | |
| SCHEMBL8653442 | 0.87 | NPY2R (0.37) | KMT2AMEN1BRPF1POLBALDH1A1 | |
| SCHEMBL8479944 | 0.87 | MAPT (0.37) | KMT2AMEN1BRPF1TP53POLB | |
| SCHEMBL8480392 | 0.87 | NPSR1 (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8652731 | 0.86 | MTTP (0.36) | KMT2AMEN1BRPF1POLBALDH1A1 | |
| SCHEMBL8668000 | 0.85 | KMT2A (0.37) | KMT2AMEN1BRPF1TP53POLB | |
| SCHEMBL8572054 | 0.84 | LMNA (0.38) | ALDH1A1MAPTCYP1A2GAACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |