Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62903 | 0.82 | MTNR1A (0.33) | MTNR1AITGB2ICAM1ITGAL | |
| SCHEMBL7831978 | 0.76 | MTNR1A (0.60) | MTNR1AKDM4E | |
| SCHEMBL6216565 | 0.71 | ITGB2 (0.39) | MTNR1AKDM4EITGB2ICAM1ITGAL | |
| SCHEMBL910176 | 0.70 | ITGB2 (0.37) | MTNR1AKDM4EITGB2ICAM1ITGAL | |
| SCHEMBL3345615 | 0.68 | ITGB2 (0.36) | KDM4EITGB2ICAM1ITGAL | |
| SCHEMBL62556 | 0.68 | ITGB2 (0.36) | MTNR1ATSHRKDM4EITGB2ICAM1 | |
| SCHEMBL6346532 | 0.68 | CTNNB1 (0.35) | MTNR1AKDM4EITGB2ICAM1ITGAL | |
| SCHEMBL3366209 | 0.68 | MTNR1A (0.59) | MTNR1AKDM4EITGB2ICAM1ITGAL | |
| SCHEMBL63619 | 0.68 | AOC3 (0.35) | — | |
| SCHEMBL6886568 | 0.66 | AOC3 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |