Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475358 | 1.00 | MDM2 (0.35) | MDM2TP53CA2CA1LMNA | |
| Hydrochloric Acid SCHEMBL6701567 | 0.88 | ATM (0.37) | MDM2KMT2APTGDR2 | |
| SCHEMBL8480629 | 0.86 | AKR1B1 (0.42) | MDM2LMNA | |
| SCHEMBL8475817 | 0.85 | AKR1B1 (0.33) | KMT2ARECQLPTGDR2 | |
| SCHEMBL8475786 | 0.85 | AKR1B1 (0.33) | KMT2ARECQLPTGDR2 | |
| SCHEMBL8480829 | 0.83 | KMT2A (0.45) | KMT2APTGDR2 | |
| SCHEMBL8481337 | 0.83 | KMT2A (0.45) | KMT2APTGDR2 | |
| SCHEMBL8523438 | 0.83 | PTGDR2 (0.36) | KMT2APTGDR2 | |
| SCHEMBL8480369 | 0.83 | NQO2 (0.39) | MDM2TP53HDAC6NPC1KMT2A | |
| SCHEMBL7029703 | 0.83 | NQO2 (0.39) | MDM2TP53HDAC6NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |