Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475817 | 1.00 | AKR1B1 (0.33) | AKR1B1KMT2AKDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6701567 | 0.88 | ATM (0.37) | AKR1B1KMT2AALDH1A1PTGDR2 | |
| SCHEMBL8481337 | 0.85 | KMT2A (0.45) | AKR1B1KMT2ACYP3A4PTGDR2 | |
| SCHEMBL8480829 | 0.85 | KMT2A (0.45) | AKR1B1KMT2ACYP3A4PTGDR2 | |
| SCHEMBL8480372 | 0.85 | MDM2 (0.35) | KMT2ARECQLPTGDR2 | |
| SCHEMBL8475358 | 0.85 | MDM2 (0.35) | KMT2ARECQLPTGDR2 | |
| SCHEMBL8523438 | 0.84 | PTGDR2 (0.36) | AKR1B1KMT2APTGDR2 | |
| Hydrochloric Acid SCHEMBL7439330 | 0.84 | KMT2A (0.44) | AKR1B1KMT2ACYP3A4PTGDR2 | |
| SCHEMBL8480629 | 0.84 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL7026066 | 0.82 | ITGB3 (0.37) | KMT2AKDM4EALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |