Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004776 | 0.83 | HTR1A (0.49) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL7004124 | 0.83 | BCHE (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL1253794 | 0.81 | MAPT (0.85) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL339374 | 0.80 | HTR1A (0.53) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL182637 | 0.80 | HTR1A (0.53) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8474968 | 0.78 | HTR1A (0.46) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8479883 | 0.77 | HTR1A (0.43) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL5253085 | 0.77 | MAPT (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL4198960 | 0.76 | MAPT (0.44) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL791853 | 0.76 | HTR1A (0.74) | MAPTMAPK1TDP1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |