Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 19/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484289 | 0.88 | LSS (0.60) | LSSMEN1KMT2A | |
| SCHEMBL8482780 | 0.81 | LSS (0.45) | LSSMEN1KMT2A | |
| SCHEMBL8479820 | 0.77 | ACHE (0.39) | LSSMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7687517 | 0.74 | LSS (0.66) | LSSMEN1KMT2A | |
| SCHEMBL7687514 | 0.74 | LSS (0.66) | LSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7684564 | 0.74 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL7681945 | 0.74 | LSS (0.76) | LSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7684573 | 0.74 | LSS (0.64) | LSSMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7679311 | 0.73 | LSS (0.75) | LSSMEN1KMT2A | |
| SCHEMBL7679390 | 0.72 | KMT2A (0.54) | MEN1KMT2AALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |