Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | FNTA | P49354 | 16/20 | 0.47 |
| ▸ | FNTB | P49356 | 16/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480647 | 1.00 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7744257 | 0.87 | FNTA (0.49) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7744133 | 0.82 | FNTA (0.47) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7744139 | 0.82 | FNTA (0.47) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8483577 | 0.82 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8483580 | 0.82 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7743534 | 0.79 | FNTA (0.58) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7743536 | 0.79 | FNTA (0.53) | FNTAFNTBPGGT1B | |
| SCHEMBL5891899 | 0.74 | CYP11B1 (0.68) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8188315 | 0.73 | CYP11B1 (0.67) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977134-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | claimed |
| US-5977134-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |