Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084346 | 1.00 | KMT2A (0.60) | KMT2AMEN1KDM4EPTPN11ALDH1A1 | |
| SCHEMBL13284337 | 0.91 | CHRM2 (0.60) | KMT2AMEN1KDM4EGNAI3CHRM2 | |
| SCHEMBL15084379 | 0.84 | MEN1 (0.55) | KMT2AMEN1KDM4EL3MBTL1TDP1 | |
| SCHEMBL15081953 | 0.82 | KMT2A (0.56) | KMT2AMEN1KDM4EPTPN11ALDH1A1 | |
| SCHEMBL12013923 | 0.82 | CHRM2 (0.68) | KMT2AMEN1GNAI3CHRM2CHRM4 | |
| SCHEMBL13284339 | 0.81 | MEN1 (0.79) | KMT2AMEN1KDM4EALDH1A1GNAI3 | |
| SCHEMBL14032713 | 0.81 | KDM4E (0.54) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL18629271 | 0.81 | ACHE (0.67) | KMT2AMEN1ALDH1A1PDE2A | |
| SCHEMBL15084345 | 0.81 | ACHE (0.67) | KMT2AMEN1ALDH1A1PDE2A | |
| SCHEMBL3696689 | 0.80 | KDM4E (0.72) | KMT2AMEN1KDM4EPTPN11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11209345-A | — | — | None | — | — | JP | disclosed |
| JP-H11209345-A | PRODUCTION OF INTERMEDIATE FOR DRUG | ONO PHARMACEUT CO LTD | 1999-08-03 | — | — | JP | disclosed |