Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8483192 | 0.95 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| Fumaric Acid SCHEMBL8480503 | 0.92 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL8477004 | 0.84 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL3596494 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL1867389 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL1867387 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL1867385 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| Hydrochloric Acid SCHEMBL8482466 | 0.80 | SSTR4 (0.46) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL8925289 | 0.79 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3MLNRADRB2 | |
| SCHEMBL5348258 | 0.79 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3MLNRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872117-A | TREATING CEREBROVASCULAR DEMENTIA, SENILE DEMENTIA, ALZHEIMER'S DEMENTIA, SEQUELAE OF ISCHEMIC ENCEPHALOPATHY AND CEREBRAL APOPLEXY | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5719150-A | ALZHEIMER'S DISEASE | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |