Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294854 | 0.87 | PTGS1 (0.36) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL28562332 | 0.87 | LMNA (0.55) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL28921885 | 0.83 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL29752624 | 0.83 | PTGS1 (0.33) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL31285795 | 0.83 | APEX1 (0.42) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL27761388 | 0.81 | — | — | |
| SCHEMBL1805336 | 0.80 | PTGS1 (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL19865717 | 0.78 | — | — | |
| SCHEMBL3137447 | 0.78 | — | — | |
| SCHEMBL30026428 | 0.78 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5944854-A | LEUCO DYES | DYSTAR TEXTILFARBEN GMBH & CO. (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5696258-A | REDUCING TO LEUCO FORM; REOXIDATION | DYSTAR TEXTILFARBEN GMBH (DE) | 1997-12-09 | — | — | US | disclosed |