Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482187 | 1.00 | MAPT (0.49) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1808904 | 0.88 | ABCB11 (0.47) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1832142 | 0.88 | MAPT (0.44) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1808903 | 0.88 | ABCB11 (0.47) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1832145 | 0.88 | MAPT (0.44) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL15711568 | 0.84 | ESR1 (0.45) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL13470060 | 0.82 | TTR (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13281270 | 0.78 | CA12 (0.39) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL31367360 | 0.78 | CYP3A4 (0.39) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL23198141 | 0.77 | SMN1; SMN2 (0.43) | MAPTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |