Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 12/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | CTRC | Q99895 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482307 | 0.85 | F2 (0.48) | ALDH1A1F2PRSS2F10CTRC | |
| SCHEMBL8481394 | 0.82 | F2 (0.40) | ALDH1A1L3MBTL1LMNAGLAHSD11B1 | |
| SCHEMBL8480305 | 0.82 | F2 (0.53) | F2PRSS2F10CTRC | |
| SCHEMBL5675812 | 0.81 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAGLAHSD11B1 | |
| SCHEMBL5674401 | 0.80 | F2 (0.50) | ALDH1A1L3MBTL1LMNAGLAF2 | |
| SCHEMBL8479194 | 0.79 | F2 (0.53) | F2PRSS2F10CTRC | |
| SCHEMBL8476682 | 0.79 | F2 (0.56) | F2PRSS2F10CTRC | |
| SCHEMBL8477586 | 0.77 | F2 (0.55) | F2PRSS2CTRC | |
| SCHEMBL5674305 | 0.77 | F2 (0.53) | F2PRSS2F10CTRC | |
| SCHEMBL8481232 | 0.75 | F2 (0.49) | F2PRSS2F10CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891909-A | Amidinohydrazones as protease inhibitors | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |