⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848248 | 1.00 | — | — | |
| SCHEMBL2253325 | 1.00 | — | — | |
| SCHEMBL18941502 | 0.95 | FAAH (0.38) | — | |
| SCHEMBL18941607 | 0.95 | TRPV1 (0.39) | — | |
| SCHEMBL18941608 | 0.95 | TRPV1 (0.39) | — | |
| SCHEMBL18941504 | 0.95 | FAAH (0.38) | — | |
| SCHEMBL18941484 | 0.95 | FAAH (0.43) | — | |
| SCHEMBL18941543 | 0.93 | FAAH (0.46) | — | |
| SCHEMBL18941613 | 0.93 | FAAH (0.46) | — | |
| SCHEMBL18941545 | 0.93 | FAAH (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207835-A1 | Alpha, Beta, Unsaturated Nitriles as Fragrances | GIVAUDAN SA (CH) | 2011-08-25 | — | — | US | claimed |
| EP-2079436-B1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2010-11-10 | — | — | EP | claimed |
| EP-2079436-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | Givaudan SA (CH) | 2009-07-22 | — | — | EP | claimed |
| WO-2008037105-A1 | ALPHA, BETA, UNSATURATED NITRILES AS FRAGRANCES | GIVAUDAN SA (CH) | 2008-04-03 | — | — | WO | claimed |
| US-20260018621-A1 | SECONDARY BATTERY AND ELECTRONIC APPARATUS | NINGDE AMPEREX TECHNOLOGY LIMITED (CN) | 2026-01-15 | — | — | US | disclosed |
| CN-109557764-B | Chemically amplified positive photosensitive resin composition, resist pattern, method for forming the same, and electronic device | 奇美实业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-3643312-A1 | 3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS | Incyte Holdings Corporation (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-2432472-B1 | 3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS | INCYTE HOLDINGS CORP (US) | 2019-10-02 | — | — | EP | disclosed |
| US-9623029-B2 | 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane- or heptane-nitrile as JAK inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-04-18 | — | — | US | disclosed |
| US-20160067253-A1 | 3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS | INCYTE HOLDINGS CORPORATION (US) | 2016-03-10 | — | — | US | disclosed |
| US-9216984-B2 | 3-[4-(7H-pyrrolo[2,3-D]pyrimidin-4-yl)-1H-pyrazol-1-yl]octane—or heptane-nitrile as JAK inhibitors | INCYTE CORPORATION (US) | 2015-12-22 | — | — | US | disclosed |
| US-9023882-B2 | 5-membered nitrogen containing heterocyclic derivatives and pharmaceutical compositions comprising the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2015-05-05 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5288315-A | Aqueous electrodepositable or alkaline paints including a bind binder and a corrosion inhibitor comprising a mono-, di- or polyazo-methine; metal substrates | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| US-4451479-A | ANTIINFLAMMATORY | AMERICAN CYANAMID COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4416824-A | Recovery of triarylboranes by forming boron-containing metal compounds | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4394321-A | CHEMICAL INTERMEDIATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4254059-A | TO PRIMARY AMINES UNDER MILD CONDITIONS USING A GROUP 8 METAL ANIONIC CATALYST COMPOSITION | ALLIED CHEMICAL CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |
| US-4038210-A | BETA-AMINO NITRILE CATALYSTS FOR POLYURETHANE PREPARATION | UNION CARBIDE CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |