Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12571535 | 0.95 | PIK3CD (0.48) | PIK3CDALDH1A1TSHRCA12CA2 | |
| SCHEMBL12571542 | 0.85 | ALDH1A1 (0.41) | PIK3CDALDH1A1TSHRCA12CA2 | |
| SCHEMBL10143907 | 0.84 | CA12 (0.61) | PIK3CDALDH1A1TSHRCA12CA2 | |
| SCHEMBL9025471 | 0.84 | PIK3CD (0.52) | PIK3CDALDH1A1CA12CA2CA3 | |
| SCHEMBL21766284 | 0.84 | PIK3CD (0.43) | PIK3CDALDH1A1TSHRCA12CA2 | |
| SCHEMBL259497 | 0.84 | PIK3CD (0.62) | PIK3CDTSHRCA12CA2CA3 | |
| SCHEMBL15894693 | 0.83 | S1PR2 (0.48) | PIK3CDDNM1CHRM2TLR8TLR7 | |
| SCHEMBL23350261 | 0.83 | CA12 (0.52) | PIK3CDALDH1A1TSHRCA12CA2 | |
| SCHEMBL2510802 | 0.81 | — | — | |
| SCHEMBL20325034 | 0.81 | CA12 (0.50) | PIK3CDALDH1A1TSHRCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888255-B1 | HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE | UNIV TEXAS (US) | 2018-07-18 | — | — | EP | disclosed |
| US-20120129240-A1 | BUFFER COMPOUNDS | SACHEM, INC. | 2012-05-24 | — | — | US | disclosed |