Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 17/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8485191 | 0.91 | LSS (0.71) | LSS | |
| SCHEMBL8484967 | 0.86 | LSS (0.66) | LSSMAPT | |
| SCHEMBL5038773 | 0.81 | LSS (0.66) | LSS | |
| SCHEMBL8478774 | 0.79 | LSS (0.69) | LSS | |
| SCHEMBL5038681 | 0.79 | LSS (0.66) | LSS | |
| SCHEMBL21113970 | 0.79 | LSS (0.57) | LSSL3MBTL1MAPT | |
| SCHEMBL5045758 | 0.79 | LSS (0.60) | LSS | |
| SCHEMBL21114055 | 0.79 | LSS (0.56) | LSSL3MBTL1MAPT | |
| SCHEMBL8759987 | 0.79 | LSS (1.00) | LSS | |
| SCHEMBL5043701 | 0.78 | LSS (0.65) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | claimed |
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |