Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018827 | 0.91 | HPGD (0.59) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8487536 | 0.84 | HTT (0.47) | ALDH1A1SMN1; SMN2HTTCYP2C9CYP2C19 | |
| SCHEMBL8487539 | 0.81 | CYP2C9 (0.33) | HTTCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL8488661 | 0.81 | IDO1 (0.39) | CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL12141690 | 0.80 | HPGD (0.79) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL487360 | 0.79 | MAPT (0.54) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8488034 | 0.78 | HPGD (0.57) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6517451 | 0.77 | MAPT (0.52) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6511474 | 0.77 | MAPT (0.52) | HPGDLMNAL3MBTL1ALDH1A1MAPT | |
| Methane SCHEMBL8806303 | 0.77 | MAPT (0.52) | HPGDLMNAL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932731-A | HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |