SCHEMBL8488661

SCHEMBL8488661

ClC(Cl)Sc1ccc(SC(Cl)Cl)cc1.Sc1ccc(S)cc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.39
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MMP2 P08253 1/20 0.30
MMP8 P22894 1/20 0.30
MMP14 P50281 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8485183 0.89 NR1H2 (0.41) IDO1CYP2C9CYP2C19HSD17B10
SCHEMBL8488666 0.89 HPGD (0.38) IDO1
SCHEMBL8779795 0.86 CYP2C9 (0.37) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL8484321 0.85 CHRNA7 (0.39) CYP2C9CYP2C19HSD17B10MMP8
SCHEMBL8489011 0.84 MAOB (0.44)
SCHEMBL8487536 0.82 HTT (0.47) CYP2C9CYP2C19HSD17B10
SCHEMBL8484991 0.81 MAPT (0.43) IDO1CYP2C9CYP2C19HSD17B10
SCHEMBL8779780 0.78 NR1H2 (0.41) CYP2C9CYP2C19HSD17B10MMP2MMP8
SCHEMBL3896041 0.76 HSD17B10 (0.52) IDO1CYP2C9CYP2C19HSD17B10MMP2
SCHEMBL8483853 0.74 EPHX1 (0.42) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed