Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.32 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806022 | 0.77 | PARP1 (0.37) | PARP1TP53FPR2PARP2PARP3 | |
| SCHEMBL64071 | 0.74 | NOTUM (0.43) | — | |
| SCHEMBL2855878 | 0.68 | TP53 (0.40) | PARP1TP53ACHE | |
| SCHEMBL4692500 | 0.68 | CHRM2 (0.38) | PARP1 | |
| SCHEMBL4692361 | 0.68 | CHRM2 (0.38) | PARP1 | |
| SCHEMBL4688219 | 0.68 | CHRM2 (0.38) | PARP1 | |
| Acetic Acid SCHEMBL16992499 | 0.68 | KDM5A (0.42) | PARP1TP53FPR2 | |
| SCHEMBL13301040 | 0.67 | ACHE (0.47) | TP53ACHE | |
| SCHEMBL22605561 | 0.67 | GPBAR1 (0.50) | — | |
| Acetic Acid SCHEMBL4688216 | 0.67 | POLB (0.43) | PARP1TP53FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |