Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485828 | 0.92 | DPP4 (0.53) | EPHX2CYP2C8TSHRLMNAMEN1 | |
| SCHEMBL18440285 | 0.92 | EPHX2 (0.52) | EPHX2CYP2C8TSHRAPEX1LMNA | |
| SCHEMBL436643 | 0.91 | DPP4 (0.52) | EPHX2CYP2C8LMNAMEN1KMT2A | |
| SCHEMBL16986143 | 0.88 | TACR1 (0.49) | EPHX2CYP2C8TSHRAPEX1OPRM1 | |
| SCHEMBL31147587 | 0.87 | TSHR (0.49) | MAOAMAOBTAAR1EPHX2CYP2C8 | |
| SCHEMBL31650281 | 0.83 | ALDH1A1 (0.42) | EPHX2CYP2C8TSHRAPEX1OPRM1 | |
| SCHEMBL435378 | 0.83 | ALDH1A1 (0.51) | EPHX2CYP2C8CNR1 | |
| SCHEMBL24309995 | 0.80 | ALDH1A1 (0.44) | MAOAMAOBTAAR1LMNACNR1 | |
| SCHEMBL433785 | 0.80 | EPHX2 (0.53) | EPHX2CYP2C8LMNAMEN1KMT2A | |
| SCHEMBL1361875 | 0.79 | TSHR (0.58) | MAOAMAOBTAAR1EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |