Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912655 | 0.85 | KMT2A (0.47) | KMT2AMTNR1AMTNR1BCA2CA9 | |
| SCHEMBL11994292 | 0.83 | MME (0.51) | PPARAPPARGCA2CA9CPA1 | |
| SCHEMBL1912534 | 0.83 | MME (0.51) | PPARAPPARGCA2CA9CPA1 | |
| SCHEMBL1912588 | 0.83 | MME (0.51) | PPARAPPARGCA2CA9CPA1 | |
| SCHEMBL1916013 | 0.80 | PPARG (0.46) | PPARAPPARGCA2CA9CPA1 | |
| SCHEMBL1916009 | 0.80 | PPARG (0.46) | PPARAPPARGCA2CA9CPA1 | |
| SCHEMBL1704171 | 0.79 | CPA1 (0.60) | CA2CA9CPA1MMECPB1 | |
| SCHEMBL1915766 | 0.79 | CPA1 (0.60) | CA2CA9CPA1MMECPB1 | |
| SCHEMBL1704913 | 0.79 | CPA1 (0.60) | CA2CA9CPA1MMECPB1 | |
| SCHEMBL30192155 | 0.79 | CTSS (0.49) | PPARAPPARGCA2CA9PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990158-A | EXTRACELLULAR MATRIX METALLOPROTEINASES INHIBITORS; ORAL ADMINISTRATION; BIOAVAILABILITY; E.G.,N-(2-(2'-(5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYLENE-OXY-2'-OXO-ETHYL)-5 -(4-METH-OXYPHENYL)OXY)PENTANOYL)PHENYLALANINE N-METHYLAMIDE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |