Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145745 | 0.87 | ASH1L (0.62) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL145474 | 0.86 | ASH1L (0.72) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL17327719 | 0.80 | ASH1L (0.57) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL4331915 | 0.80 | ASH1L (0.60) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL23675210 | 0.79 | ASH1L (0.71) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL30776866 | 0.79 | ASH1L (0.71) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL29994513 | 0.79 | ASH1L (0.71) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL5609122 | 0.78 | NR4A2 (0.59) | ASH1LNPC1IMPDH2ALDH1A1MAPT | |
| SCHEMBL19475912 | 0.77 | NPC1 (0.62) | ASH1LNPC1IMPDH2PDGFRBEIF2AK2 | |
| SCHEMBL30954379 | 0.77 | PRKAB2 (0.55) | NPC1CA1CA2PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936098-A | Process for producing indoline compounds and intermediates for the production of the same | TOKYO TANABE COMPANY LIMITED (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0810214-A1 | PROCESS FOR PRODUCING INDOLINE COMPOUNDS AND INTERMEDIATES FOR THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |