Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 13/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 13/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.36 |
| ▸ | MTR | Q99707 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666056 | 0.96 | MTR (0.34) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8503629 | 0.92 | MTR (0.31) | SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8480406 | 0.84 | SCN1A (0.36) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8483380 | 0.81 | MTR (0.37) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8666044 | 0.80 | MTR (0.35) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8717828 | 0.77 | MTTP (0.41) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8503024 | 0.76 | AOC3 (0.32) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL6187970 | 0.76 | MTTP (0.47) | SCN1ASCN5ASCN9AMTR | |
| SCHEMBL8484923 | 0.76 | MTR (0.42) | SCN1ASCN5ASCN9AMTRAOC3 | |
| SCHEMBL8666040 | 0.74 | MTTP (0.40) | SCN1ASCN5ASCN9AMTRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |