Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLR1A | O95602 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489699 | 0.92 | ALDH1A1 (0.37) | KMT2APOLR1AALDH1A1KDM4EHPGD | |
| SCHEMBL9388319 | 0.89 | EIF4EBP1 (0.33) | KMT2APOLR1AALDH1A1KDM4EEIF4EBP1 | |
| SCHEMBL8488726 | 0.88 | ALDH1A1 (0.37) | KMT2APOLR1AALDH1A1KDM4EHPGD | |
| SCHEMBL8488936 | 0.87 | NAMPT (0.38) | KMT2A | |
| SCHEMBL9221939 | 0.84 | HDAC1 (0.34) | KMT2AALDH1A1KDM4EHPGDEIF4EBP1 | |
| SCHEMBL8485127 | 0.84 | EIF4EBP1 (0.34) | KMT2APOLR1AALDH1A1KDM4EEIF4EBP1 | |
| SCHEMBL9388324 | 0.84 | KMT2A (0.35) | KMT2AALDH1A1KDM4EEIF4EBP1MEN1 | |
| SCHEMBL9389115 | 0.80 | NAMPT (0.36) | — | |
| SCHEMBL8488360 | 0.80 | NAMPT (0.40) | KMT2AALDH1A1KDM4EEIF4EBP1MEN1 | |
| SCHEMBL8485856 | 0.79 | GAA (0.43) | KMT2AALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |