SCHEMBL8485

SCHEMBL8485

c1ccc(CC2COCCO2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM3 P20309 1/20 0.40
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
GRM2 Q14416 1/20 0.39
HTR5A P47898 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAPT P10636 1/20 0.38
DRD4 P21917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27469603 0.98 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3CHRM2CHRM4
Hydrochloric Acid SCHEMBL12503316 0.98 KDM4E (0.41) SLC6A2SLC6A4SLC6A3CHRM2CHRM4
SCHEMBL873444 0.83 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3GRM2TAAR1
SCHEMBL51254 0.83 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3GRM2TAAR1
SCHEMBL2186411 0.83 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3GRM2TAAR1
SCHEMBL1957441 0.82 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3GRM2TAAR1
SCHEMBL23146225 0.81 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM3KDM4E
SCHEMBL5311567 0.81 ALDH1A1 (0.42) CHRM2CHRM4CHRM5CHRM3KDM4E
SCHEMBL23146418 0.81 CHRM2 (0.38) CHRM2CHRM4CHRM5CHRM3KDM4E
SCHEMBL450127 0.81 DRD4 (0.53) SLC6A2SLC6A4SLC6A3TAAR1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26576 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
CN-122036610-A Synthesis method of central chiral aza seven-membered bridged aromatic compound containing chiral axis 浙江大学 2026-05-15 CN claimed
US-12590100-B2 Tetrahydro-spiroindoline-pyrrolopyrrole-triones inhibitors of the NRF2-β-TrCP interaction for use in the treatment of fatty liver disease UNIV MADRID AUTONOMA (ES) 2026-03-31 US claimed
US-20260069599-A1 INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 AND PHOSPHOINOSITIDE 3-KINASE UNIV NEBRASKA (US) 2026-03-12 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-119725417-A Composite positive electrode material, preparation method thereof, positive electrode plate, battery and power utilization device 宁德时代新能源科技股份有限公司 2025-03-28 CN claimed
WO-2024251133-A1 HETEROCYCLIC COMPOUND AS α5-GABAA RECEPTOR MODULATOR AND USE THEREOF 武汉人福创新药物研发中心有限公司 2024-12-12 WO claimed
EP-4277620-B1 TETRAHYDRO-SPIROINDOLINE-PYRROLOPYRROLE-TRIONES INHIBITORS OF THE NRF2-BETA-TRCP INTERACTION FOR USE IN THE TREATMENT OF FATTY LIVER DISEASE UNIV MADRID AUTONOMA (ES) 2024-12-04 EP claimed
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN claimed
CN-118726289-A (2S, 3R) selective carbonyl reductase mutant VAF and method for preparing aromatic alpha-amino-beta-hydroxy ester chiral intermediate by using same 浙江工业大学 2024-10-01 CN claimed
EP-0004366-B1 HAIR DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1981-07-08 EP claimed
US-4238496-A ANTIALLERGENS BOEHRINGER INGELHEIM GMBH (DE) 1980-12-09 US claimed
US-4234580-A INSECTICIDES; MITACIDES UNION CARBIDE CORPORATION (US) 1980-11-18 US claimed
US-4221807-A ADRENERGIC BLOCKING AGENTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-09-09 US claimed
US-4217305-A HYPOTENSIVE AGENTS, ADRENERGIC BLOCKING AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1980-08-12 US claimed
US-4177272-A HYPOTENSIVE, VASODILATION, PARKINSON'S DISEASE SCIENCE UNION ET CIE (FR) 1979-12-04 US claimed
US-4169894-A INSECTICIDES, MITICIDES, NEMATOCIDES UNION CARBIDE CORPORATION (US) 1979-10-02 US claimed
US-4166864-A MITICIDES, INSECTICIDES UNION CARBIDE CORPORATION (US) 1979-09-04 US claimed
US-4003746-A Organic heterocyclic and thioaryl phosphines in silver halide emulsions and developers therefor E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-18 US claimed
US-3967835-A Pressure-sensitive copying material HODOGAYA CHEMICAL CO., LTD. (JA) 1976-07-06 US claimed