Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | NSD2 | O96028 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797517 | 0.86 | HEXA (0.40) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL4158909 | 0.81 | KDM4E (0.49) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL15018068 | 0.80 | HEXA (0.41) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL11881952 | 0.77 | MAPT (0.53) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL11790961 | 0.77 | KDM4E (0.35) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL15018691 | 0.77 | NPC1 (0.49) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL1268568 | 0.77 | ALDH1A1 (0.38) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL15018437 | 0.76 | HEXA (0.45) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL1773296 | 0.73 | NSD2 (0.46) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL15018655 | 0.73 | NR1I2 (0.47) | KDM4EMAPTHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922086-A | OXIDATION COLOR DYES FOR HAIR WITH PERMIDINE COUPLERS AND DEVELOPERS | CLARIANT GMBH (DE) | 1999-07-13 | — | — | US | disclosed |