Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | FNTA | P49354 | 10/20 | 0.39 |
| ▸ | FNTB | P49356 | 10/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499175 | 0.92 | CYP11B1 (0.41) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8500957 | 0.90 | FNTA (0.41) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8497691 | 0.90 | FNTA (0.39) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8582438 | 0.89 | FNTA (0.40) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8606558 | 0.88 | FNTA (0.41) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8501334 | 0.88 | FNTA (0.40) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8582869 | 0.87 | FNTA (0.39) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8494113 | 0.87 | CYP11B1 (0.42) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8503532 | 0.87 | FNTA (0.42) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8635750 | 0.86 | FNTA (0.41) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012912-A1 | THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH | YUHAN CORPORATION (KR) | 1999-03-18 | — | — | WO | disclosed |