SCHEMBL8499175 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	CYP11B1	P15538	3/20	0.41

▸	CYP11B2	P19099	3/20	0.41

▸	FNTA	P49354	9/20	0.41

▸	FNTB	P49356	9/20	0.41

▸	PGGT1B	P53609	8/20	0.41

▸	SMN1; SMN2	Q16637	2/20	0.40

▸	KDM4E	B2RXH2	1/20	0.40

▸	POLB	P06746	1/20	0.40

▸	TSHR	P16473	1/20	0.40

▸	HSD17B10	Q99714	1/20	0.40

▸	ALDH1A1	P00352	1/20	0.38

▸	MAPT	P10636	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8500957	0.93	FNTA (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8497691	0.93	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8485205	0.92	CYP11B1 (0.40)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8582438	0.90	FNTA (0.40)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8582869	0.90	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8501334	0.90	FNTA (0.40)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8606558	0.90	FNTA (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8493626	0.89	CYP11B1 (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8494113	0.88	CYP11B1 (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8503532	0.88	FNTA (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999012912-A1	THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH	YUHAN CORPORATION (KR)	1999-03-18	—	—	WO	disclosed