Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 13/20 | 0.78 |
| ▸ | DRD2 | P14416 | 11/20 | 0.78 |
| ▸ | DRD3 | P35462 | 10/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8484199 | 0.99 | DRD4 (0.77) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| SCHEMBL8482373 | 0.88 | DRD4 (1.00) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| SCHEMBL8482386 | 0.87 | DRD4 (0.84) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| SCHEMBL8480606 | 0.87 | DRD4 (0.62) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL8484909 | 0.86 | DRD4 (0.82) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL8480602 | 0.82 | DRD4 (0.56) | DRD4DRD2DRD3ACHEBACE1 | |
| SCHEMBL8121641 | 0.81 | DRD4 (0.85) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| SCHEMBL8482381 | 0.81 | DRD4 (0.72) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL8484196 | 0.80 | DRD4 (0.70) | DRD4DRD2DRD3SIGMAR1KCNH2 | |
| SCHEMBL8484752 | 0.77 | GABRA1 (0.46) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939436-A | Five-membered heteroaromatic compounds as dopamine receptor subtype ligands | MERCK SHARP & DOHME LTD. (GB) | 1999-08-17 | — | — | US | disclosed |