Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SDHA | P31040 | 2/20 | 0.52 |
| ▸ | CALML3 | P27482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342936 | 0.89 | MAOA (0.59) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL7945883 | 0.85 | MAOA (0.54) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL7947020 | 0.84 | MAOA (0.56) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL7949639 | 0.84 | MAOA (0.55) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL10258874 | 0.80 | MAOA (0.61) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL10259390 | 0.79 | MAOA (0.60) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL10259129 | 0.79 | MAOA (0.60) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL15506988 | 0.79 | MAOA (0.59) | MAOATHRBMAOBPTGS1SDHA | |
| SCHEMBL6649952 | 0.79 | MAOA (0.66) | MAOAMAOBPTGS1SDHACALML3 | |
| SCHEMBL1393599 | 0.79 | MAOA (0.55) | MAOATHRBMAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003846-A1 | TRICYCLICALLY SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |